Proton Radiotherapy Verification and Dosimetry Applications

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Dr Michela Esposito

Dr. Michela Esposito

Michela has a research interest in radiation detectors applied to medical and biological imaging.

She joined the University of Lincoln in February 2013 as Research Fellow, to work of the development of the PRaVDA instrument.

Michela has a BSc and an MRes in Physics from University of Naples (Italy).

Since 2009 Michela has been working on the development of imaging systems for medical and biological applications, as well as testing and characterisation of the detection devices in an early stage of their development.

Between June 2009 and December 2010, as Research Associate at the Italian Institute for Nuclear Physics (INFN), Michela developed a spectroscopic imaging system for light charged particles, to be used in biological applications such as beta autoradiography and electron microscopy. She also contributed to the development of a compact gamma camera for sentinel lymph node imaging. In late 2010 Michela joined the University of Surrey as Research Assistant, where developed a single imaging platform based on a large area CMOS Active Pixel Sensor for multi-modality imaging in pre-clinical science.

Michela’s research activity focuses on the simulation, development and characterisation of ionising and non-ionising radiation detectors for medical and biological imaging applications.


List of publications:


M. Esposito, T. Anaxagoras, A. C. Konstantinidis, Y. Zheng, R. D. Speller, P. M. Evans, N. M. Allinson, K. Wells, “Performance of a novel wafer scale CMOS active pixel sensor for bio-medical imaging”, Physics in Medicine and Biology 06/2014; 59(13):3533. DOI 10.1088/0031-9155/59/13/3533

G. Poludniowski, N. M. Allinson, T. Anaxagoras, M. Esposito, S. Green, S. Manolopoulos, J. Nieto-Camero, D. J. Parker, T. Price, P. M. Evans, “Proton-counting radiography for proton therapy: a proof of principle using CMOS APS technology”, Physics in Medicine and Biology 05/2014; 59(11):2569. DOI:10.1088/0031-9155/59/11/2569

 M. Esposito, T. Anaxagoras, J. Larner, N.N. Allinson, K. Wells, “14C autoradiography with a novel wafer scale CMOS Active Pixel Sensor”, Journal of Instrumentation 01/2013; 8:C01011. DOI:10.1088/1748-0221/8/01/C01011

M. Esposito, A.Bailey, J.Newcombe, T.Anaxagoras, N.M.Allinson, K.Wells, “CMOS APS in pre-clinical science: Next generation disruptive technology for multi-modality imaging”, Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), vol., no., pp.1910,1913, Oct. 27 2012-Nov. 3 2012 DOI: 10.1109/NSSMIC.2012.6551442

M. Esposito, T.Anaxagoras, O.Diaz, K.Wells, N.M.Allinson, "Radiation hardness of a large area CMOS active pixel sensor for bio-medical applications," Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2012 IEEE , vol., no., pp.1300,1304, Oct. 27 2012-Nov. 3 2012

DOI: 10.1109/NSSMIC.2012.6551318

M. Esposito, J. Newcombe, T. Anaxagoras, N. M. Allinson,  K. Wells, “Using a large area CMOS APS for direct chemiluminescence detection in Western blotting electrophoresis”, Proc. SPIE 8317, Medical Imaging 2012: Biomedical Applications in Molecular, Structural, and Functional Imaging, 831710 (March 23, 2012); DOI:10.1117/12.911615.

A. Konstantinidis, T. Anaxagoras, M. Esposito,  N. Allinson ; R. Speller, “DynAMITe: a prototype large area CMOS APS for breast cancer diagnosis using x-ray diffraction measurement”,  Proc. SPIE 8313, Medical Imaging 2012: Physics of Medical Imaging, 83135H (February 23, 2012); DOI:10.1117/12.911541.

 M. Esposito, T. Anaxagoras, A. Fant, K. Wells, A. Konstantinidis, J.P.F. Osmond,P.M. Evans, R.D. Speller, N.M. Allinson, “DynAMITe: A wafer scale sensor forbiomedical applications”. Journal of Instrumentation, 6 (12), 2012.doi:10.1088/1748-0221/6/12/C12064

 M. Esposito, J. Newcombe, K. Wells, "Western blotting electrophoretic sequencing: First images with a room temperature CMOS detector”,  Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE , vol., no., pp.2491,2494, 23-29 Oct. 2011

DOI: 10.1109/NSSMIC.2011.6152675

M. Esposito, G. Mettivier and P. Russo, “14C autoradiography with an energy-sensitivesilicon pixel detector”,  Physics in Medicine and Biology, 56 1947 - 1965, 2011. DOI:10.1088/0031-9155/56/7/003

M. Esposito, J. Jakubek, G. Mettivier, S. Pospisil, P. Russo, and J. Solc, “Energy sensitive Timepix silicon detector for electron imaging”. Nuclear Instruments and Methods in Physics Research Section A 662 458 461, 2011. doi:10.1016/j.nima.2011.01.148

P. Russo, A. S. Curion, G. Mettivier, M. Esposito, M. Aurilio, C. Caraco, L. Aloj, and S. Lastoria, “Evaluation of a CdTe semiconductor based compact gamma camera or sentinel lymph node imaging”, Medical Physics 38 1547 1563, 2011. doi:10.1118/1.3555034







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